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Comprehensive analysis of clinical research and evidence*
Sleep Science By Menopause Science
Declining estrogen disrupts your natural sleep-wake cycle, while anxiety about life changes and physical discomfort create a perfect storm of sleeplessness.*
Research Summary
Research demonstrates that sleep disruption affects approximately 61% of women during the menopausal transition, often beginning during perimenopause and persisting beyond the final menstrual period. Clinical studies specifically in menopausal and postmenopausal women have shown that targeted natural sleep support can significantly improve sleep quality, reduce anxiety, and support healthy circadian rhythms during hormonal transitions.*
Research at a Glance
| Ingredient | Population Studied | Studied Benefit(s) | Research Link |
|---|---|---|---|
| Vitamin D3 | Adults18-65 | Bone health support | |
| Melatonin | Perimenopausal Women | Systematic review: Melatonin may improve sleep quality in menopausal women with pre-existing sleep impairment | View Study |
| Valerian extract | Postmenopausal women with insomnia | RCT: 530mg valerian extract twice daily for 4 weeks significantly improved sleep quality | View Study |
| Chamomile & Lavender | Postmenopausal women | RCT: Both herbal teas significantly reduced anxiety and depression compared to the control group | View Study |
| Chamomile extract | Various populations with anxiety | Systematic review: 9 out of 10 studies show chamomile may effectively reduce anxiety symptoms | View Study |
| Lavender aromatherapy | Older adults | RCT: 30-day lavender inhalation significantly reduced depression, anxiety, and stress | View Study |
Plain Language Summary
Melatonin is well-tolerated in menopausal women with no reports of serious adverse effects in clinical trials. Valerian has a centuries-long history of traditional use, and recent clinical studies have confirmed its safety in postmenopausal women. Chamomile and lavender are generally recognized as safe with minimal side effects. Some women may experience mild drowsiness the next morning when first starting. If this occurs, consider taking it earlier in the evening. Not recommended during pregnancy or breastfeeding. Always consult your healthcare provider before starting any new supplement regimen.*
Key Citations
Primary Research in Women In Phases of Menopause:
- Sleep, melatonin, and the menopausal transition: what are the links? Sleep Sci. 2017;10(1):11-18. PMC: 5611767
- Effect of valerian on sleep quality in postmenopausal women: a randomized placebo-controlled clinical trial. Menopause. 2011;18(9):951-5. PubMed: 21775910
Supporting Anxiety & Sleep Research:
- Comparison of the effectiveness of lavender and chamomile herbal tea on anxiety and depression in postmenopausal women. Women's Health Bull. 2022;9(3):172-180. Clinical Trial
- The effect of oral chamomile on anxiety: a systematic review of clinical trials. Clin Nutr Res. 2024;13(2):139-147. PMC: 11109927
- Lavender and the nervous system. Evid Based Complement Alternat Med. 2013;2013:681304. PMC: 3612440
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Shop NowThese statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider before starting any new supplement regimen, especially if you have pre-existing health conditions or are taking medications.
The research cited represents studies conducted on individual ingredients and may not reflect the specific formulation of this product. Individual results may vary based on sleep hygiene, stress levels, health status, and other factors. The research cited represents potential benefits and does not guarantee specific outcomes for all users.